Nutritional Evaluation of Satwa, An Ayurvedic Formulation of Three Tinospora Species from India
Abstract
Guduchi (Tinospora sp.) is referred to as one of the most versatile rejuvenating herb in Ayurvedic system of medicine. Although the literature is available for various medicinal uses of Tinospora sp., the systematic nutritional analysis of the plant has not yet been reported. In the present study, we report the nutritional characteristics of Satwa, an ayurvedic formulation, prepared from three different species of Tinospora viz. T. cordifolia, T. sinensis and Neem-guduchi (T. cordifolia growing on Neem Tree). As per ayurvedic literature, the satwa is regarded as aqueous extractable solid substances with starchy material. In the present studies, satwa from Neem-guduchi was found to be significantly rich in carbohydrates while satwa from T. sinensis was found to be rich in starch. The HPTLC profiling revealed characteristic concentration of one of the constituents of satwa from Neem-guduchi. The HPTLC profile and the nutritional parameters can be used for quality control procedures to prevent adulterations and to encourage the use of most potent species of guduchi. Based on the earlier studies from the authors’ laboratory, it is recommended to use the satwa made from Neem-guduchi and a supplement of omega 3-fatty acids for enhanced hepatocorrective and hepatoprotective actions of the formulation.
Keywords
References
Tripathi L, Tripathi J: Role of biotechnology in medicinal plant. Tropical Journal of Pharmaceutical Research, 2003, 2: 243-253.
Archana, Jatawa S, Paul R, Tiwari A: Indian medicinal plants: A rich source of natural immune-modulator. International Journal of Pharmacology, 2011, 7: 198-205.
Mahima, Rahal AK, Deb R, Latheef SK, Samad HA: Immunomodulatory and therapeutic potential of herbal, traditional, indigenous and ethanoveterinary medicine. Pakistan Journal of Biological Sciences, 2012, 15: 754-774.
Dhama K, Chakraborty S, Mahima, Wani MY, Verma AK: Novel and emerging therapies safeguarding health of humans and their companion animals: A Review. Pakistan Journal of Biological Sciences, 2013, 16: 101-111.
Shulz,Volker, Hänsel R, Blumenthal M: Medicinal plants, Phytomedicines and Phytotherapy: A physicians’ guide to herbal medicine. Vol 4. New York: 2001.
Nadkarni KM: Indian Materia Medica. Vol 1. Bombay (India): Popular Prakashan; 1993.
Badar VA, Thawani VR, Wakode PT, Shrivastava MP, Gharpure KJ, Hingorani LL, Khiyani RM: Efficacy of Tinospora cordifolia in allergic rhinitis. Journal of Ethnopharmacology, 2005, 96(3): 445-449.
Bafna PA, Balaraman R: Anti-ulcer and anti-oxidant activity of pepticare, a herb mineral formulation. Phytomedicine, 2005, 12(4): 264-270.
Nair PK, Rodriguez S, Ramachandran R, Alamo A, Melnick SJ, Escalon E, Garcia PI Jr, Wnuk SF, Ramachandran C: Immune stimulating properties of a novel polysaccharide from the medicinal plant Tinospora cordifolia. International Journal of Immunopharmacology, 2004, 4(13): 1645-1659.
Singh SM, Singh N, Shrivastava P: Effect of alcoholic extract of Ayurvedic herb Tinospora cordifolia on the proliferation and myeloid differentiation of bone marrow precursor cells in a tumor-bearing host. Fitoterapia, 2006, 77(1): 1-11.
Sinha K, Mishra NP, Singh J, Khanuja SPS: Tinospora cordifolia (guduchi), a reservoir plant for therapeutic applications: A Review. Indian Journal of Traditional Knowledge, 2004, 3: 257-270.
Pendse V, Mahavir MM, Khanna KC, Somani SK: Anti-inflammatory and related activity of Tinospora cordifolia (Neemgiloe). Indian Drugs, 1981, 19: 14-71.
Singh SS, Pandey SC, Srivastava S, Gupta VS , Patro B , Ghosh AC: Chemistry and medicinal properties of Tinospora Cordifolia (Guduchi). Indian Journal of Pharmacology, 2003, 35: 83-91.
Thatte VM, Rao SG, Dahanukar SA: Tinospora cordifolia induces colony-stimulating activity in serum. Journal of Postgraduate Medicine, 1994, 40: 202-203.
Thatte VM, Chhobria SC, Karandikar SM, Dahanukar SM: Protective effects of Indian medicinal plants against cyclophosphamide neutropenia. Journal of Postgraduate Medicine, 1987, 33: 185-188.
Chavan T, Khadke S, Harke S, Ghadge A, Karandikar M, Pandit V, Ranjekar P, Kulkarni O, Kuvalekar A: Satwa from three Tinospora species exhibits differential hepatoprotective activity against repeated acetaminophen dosing in rats. International Journal of Pharmacy Research, 2013, 6: 123-128.
Mahima, Rahal AK, Prakash A, Verma A, Kumar V, Roy D: Proximate and elemental analysis of Tinospora cardifolia stem. Pakistan Journal of Biological Sciences 2014, 17(5): 744-745.
Nile SH , Khobragade CNN: Determination of Nutritive Value and Mineral Elements of some Important Medicinal Plants from Western Part of India. Journal of Medicinal Plants, 2009, 8(5): 79-88.
Khandal S, Sharma K. Rasa Bhaishajya KalpanaVignana. Edn 1st Vol 1. India: Publication Scheme New Delhi; 1992.
Sawhney SK, Randhir S: Introductory practical Biochemistry. India: Narosa Publication House; 2006.
Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the folin phenol reagent. Journal of Biological Chemistry, 1951, 193(1): 265-275.
Mattoo RL: Influence of sodium chloride on the colorimetric determination of protein in plant tissues rich in phenols- phenolases. Indian Journal of Biochemistry, 1970, 7(1): 82-83.
Hedge JE, Hofreiter BT: Estimation of carbohydrate. In Carbohydrate Chem. Edited by Whistler RL, Bemiller, JN: New York: Academic Press; 1962.
Dubois M, Gilles KA, Hamilton JK, Rebers PA, Smith F: Colorimetric Method for Determination of Sugars and Related Substances. Analytical Chemistry, 1956, 26: 350-356.
Krishnaveni S, Balasubramanian T, Sadasivam S: Sugar distribution in sweet stalk sorghum. Food Chemistry, 1984, 15(3): 229-232.
Thyumanavan B, Sadasivam S: Physicochemical basis for the preferential uses of certain rice varieties. Plant Foods for Human Nutrition, 1984, 34: 253-259.
Folch J, Lees M , Sloane-Stanely GH: A simple method for the isolation and purification of total lipids from animal tissues. Journal of Biological Chemistry, 1957, 226: 497-509.
Raghuramula N, Madhavan NK, Kalyanasundaram S: A Manual of Laboratory Techniques. National Institute of Nutrition. Hyderabad: Indian Council of Medical Research, 2003.
Anonymous: The Ayurvedic formulary of India. Edn. 2nd Part I. Ministry of Health and Family Welfare. New Delhi, Govt. of India: 2003.
Sharma R, Amin H, Shukla VJ, Kartar D, Galib R, Prajapati PK: Quality control evaluation of Guduchi Satva (solid aqueous extract of Tinospora cordifolia (Willd.) Miers): An herbal formulation. International Journal of Green Pharmacy, 2013, 7: 258-263.
Chavan T, Khadke S, Harke S, Ghadge A, Karandikar M, Pandit V, Ranjekar P, Kulkarni O, Kuvalekar A: Hepatoprotective effect of polyunsaturated fatty acids against repeated subacute acetaminophen dosing in rats. International Journal of Pharma and Biosciences, 2013, 4(2): 286-295.
Nasreen S, Radha R, Jayashree N, Selvaraj B, Rajendran A: Assessment of quality of Tinospora cordifolia (willd.) Mier. (Menispermacea): Pharacognostical and phyto-physicolochemical profile. International Journal of Comprehensive Pharmacy, 2010, 5(3): 1-4.
Geeta K, Kumari S: Nutritional Evaluation of Giloe (Tinospora cordifolia) Extract Incorporated Energy Dense Food Products. Indian Journal of Research, 2013, 2(9): 41-43.
Hussain J, Khan AL, Rehman N, Hamayun M, Shinwari ZK, Ullah W, Lee IJ: Assessment of herbal products and their composite medicinal plants through proximate and micronutrient analyses. Journal of Medcinal Plants Research, 2009, 3: 1072-1077.
Nordeid MB, Hatloy A, Folling M, Lied E, Oshaug A: Nutrient composition and nutritional importance of green leaves and wild food resources in an agricultural district Koutiala in southern Mali. International Journal of Food Sciene and Nutrition, 1996, 47: 455-468.
Kutbay HG, Ok T: Foliar N Resorbtion and nutrient levels along an elevational gradient Zelkova carpinifolia (Pall.) C. Koch subspecies yomraensis. Annals of Agricultural and Biological Research, 2001, 6: 1-8.
Sharma R, Amin H, Galib R, Prajapati PK: Seasonal variations in physicochemical profiles of Guduchi Satva (starchy substance from Tinospora cordifolia [Willd.] Miers). Journal of Ayurvedic and Integrative Medicine, 2013, 4(4): 193-197.
DOI: http://dx.doi.org/10.14259%2Fpm.v2i2.132
Refbacks
- There are currently no refbacks.




