Anti-Inflammatory And Antipyretic Activities Of Allamanda cathartica L. Leaves In Rats
Abstract
The ethanolic extract of Allamanda cathartica L. leaves at doses of 100, 250 and 500 mg/kg was investigated for anti-inflammatory and antipyretic activities on carrageenan induced rat paw edema and brewer’s yeast-induced pyrexia in rats. The ethanolic extract of Allamanda cathartica leaves was investigated for anti-inflammatory (carrageen induced rat paw edema) in the rats. In the systemic edema of the rat paw the extract significantly(P<0.05) suppressed the development of paw edema. The anti pyretic effect of ethanolic extract of Allamanda cathartica yeast induced pyrexia rat the extract significantly (P<0.01) decreased in body temperature. The results obtained in this study showed that the leaves of Allamanda cathartica have pharmacological properties which provide a basis for the traditional use of the plant.
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DOI: http://dx.doi.org/10.14259%2Fpm.v2i1.85
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